杀手（约翰·库萨克）接到神秘商人（罗伯特·德尼罗）的委托，去取回一个重要的包裹。他来到了交易场所汽车旅馆，与一个金发美女不期而遇，事情突然变得棘手起来，包裹里究竟装了什么，神秘美女又是什么背景，让杀手陷入了前所未遇 的绝境。
Jack (Cusack) is asked to pick up a bag and deliver it to Dragna (DeNiro). Jack is told not to look in the bag but to just deliver it for a handsome reward. The movie starts with Jack already having the bag and having to wait for Dragna to pick it up at a run-down motel. Characters already staying at the motel, the motel manager, and the police all play a part in Jack's time protecting the bag for Dragna.
Throughout the movie, questions arise such as what is in the bag, who is out to kill Jack for the bag, and when will Dragna get there. This movie also has a ton of memorable characters such as Ned (Glover) the creepy motel manager, Rivka (DeCosta) the hooker, a pimp, a Russian mobster who is a "little person", Dragna (DeNiro), the Sheriff, and of course the bag protector, Jack (Cusack).
